Correlation of Serum Hepatitis C Viral Load and Immunobiochemical biomarkers in Combined Therapy Treated Patients
Paper ID : 1004-ISCBAS
Authors
Fathia Ahmed Ibrahim *1, Maha Ghazi Soliman2, Hanaa Abdelfattah Elsaied3
1Laboratory Section, Ministry of Health, Giza, Egypt
2zoology-entamology, faculty of science, al-azhar university, Cairo, Egypt
3medical microbiology, National organization for drug control and research, Cairo, Egypt
Abstract
Hepatitis C virus (HCV) infection is a major global disease that frequently causes chronicity and has the potential to cause liver failure and it is widespread in Egypt. The current study aimed to explore the potential correlation between quantitatively detected virus C load using quantitative reverse‐transcription polymerase chain reaction (qRT‐PCR) assay and some immunological, biochemical and hematological biomarkers. Results from 600 HCV-positive people age ranged between 25 and 55 years old were analyzed using the Prism, a computer program (Graph Pad software. Version 5, San Diego, CA), concluded that, there were a significant relation between HCV viral load and immuno-biological biomarkers. Also, the present study referred to the efficacy of Sofosbuvir/Daclatsvir combined therapy where 100% SVR in all patients.
Keywords
HCV, correlation, immunological, biochemical, hematological, sofosbuvir, daclatsvir
Status: Abstract Accepted (Poster Presentation)